|Classification Name:||Dressing Framycetin Gauze BP|
|Manufacturer:||Hoechst Marion Roussel Ltd.|
Sofra-Tulle consists of a cotton leno-weave fabric, impregnated with a base composed of white soft paraffin, anhydrous lanolin, and 1.0% w/w framycetin sulphate.
Framycetin is an antibiotic of the aminoglycoside group with a wide spectrum of antibacterial activity. Organisms sensitive to framycetin include Staphylococcus aureus, Escherischia coli, Klebsiella species, and some strains of Pseudomonas aeruginosa; it is not active against yeasts, fungi or viruses.
The dressing is used as a primary wound contact layer in the management of infected wounds, combining low adherence with antimicrobial activity.
Sofra-Tulle may be used in the management of wounds, including minor traumatic injuries, ulcers, burns, and other lesions that are clinically infected by organisms shown to be sensitive to framycetin.
Sofra-Tulle is contra-indicated in patients who are allergic to lanolin, or who have previously demonstrated a sensitivity to framycetin, neomycin, or any other chemically related product. The dressing should not be used in the treatment of wounds that are free of clinical infection, or infected by organisms that are resistant to the antibiotic.
The wound should be cleansed with a suitable sterile solution, such as normal saline; a single layer of Sofra-Tulle should then be applied and covered with an absorbent pad, held in place with tape or a bandage, as appropriate. When used to dress ulcers, Sofra-Tulle should be shaped to fit the crater and not allowed to extend over the surrounding skin.
The frequency of dressing changes will depend entirely upon the nature of the wound, but infected wounds that are exuding heavily should be dressed at least once a day.
Cross-sensitisation to framycetin may occur in patients known to be allergic to chemically related antibiotics (such as neomycin and kanamycin). In normal use, absorption of the antibiotic from Sofra-Tulle is negligible; however, where large areas of the body are being treated, the possibility of ototoxicity caused by prolonged application should be considered.
Pack Shot Sofra-Tulle is presented individually wrapped in an aluminium peel pouch, manufactured under aseptic conditions.
Sofra-Tulle should be stored in a cool place.
10 cm × 10 cm*
10 cm × 30 cm
* available on Drug Tariff.
Prescription Only Medicine [POM]
1. Milwidsky J, Soframycin unitulle in general practice; A report of forty-three patients, Medical Proceedings, 1971, 17, (3), 42-43.
2. Howell RW, Industrial burns and scalds, Nursing Mirror, 1975,
February 13th 51-54.
|Revision Author||Dr S. Thomas|
This datacard has been prepared from data provided by the manufacturer and/or from published literature.